Monday, July 20, 2009

Drugs That Block Blood Vessel Growth May Help Obesity

Zafgen, a biopharmaceutical startup based in Cambridge, MA, is attacking obesity the way that cancer researchers have been attacking tumors for decades: using drugs that interfere with its blood supply.
The fat cells that make up adipose tissue can't grow without blood vessels to nourish them. Zafgen, a startup based in Cambridge, MA, is developing obesity drugs that starve fat tissue by blocking blood-vessel proliferation. These drugs, which were originally designed to halt tumor growth, cause dramatic weight loss in obese mice.

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